Nature Communications (May 2022)
Wireless implantable optical probe for continuous monitoring of oxygen saturation in flaps and organ grafts
- Hexia Guo,
- Wubin Bai,
- Wei Ouyang,
- Yihan Liu,
- Changsheng Wu,
- Yameng Xu,
- Yang Weng,
- Hao Zang,
- Yiming Liu,
- Lauren Jacobson,
- Ziying Hu,
- Yihang Wang,
- Hany M. Arafa,
- Quansan Yang,
- Di Lu,
- Shuo Li,
- Lin Zhang,
- Xun Xiao,
- Abraham Vázquez-Guardado,
- Joanna Ciatti,
- Elizabeth Dempsey,
- Nayereh Ghoreishi-Haack,
- Emily A. Waters,
- Chad R. Haney,
- Amanda M. Westman,
- Matthew R. MacEwan,
- Mitchell A. Pet,
- John A. Rogers
Affiliations
- Hexia Guo
- Department of Materials Science and Engineering, Northwestern University
- Wubin Bai
- Department of Materials Science and Engineering, Northwestern University
- Wei Ouyang
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Yihan Liu
- Department of Applied Physical Sciences, University of North Carolina at Chapel Hill
- Changsheng Wu
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Yameng Xu
- The Institute of Materials Science and Engineering, Washington University in St. Louis
- Yang Weng
- Department of Materials Science and Engineering, Northwestern University
- Hao Zang
- Department of Materials Science and Engineering, Northwestern University
- Yiming Liu
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Lauren Jacobson
- Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine
- Ziying Hu
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Yihang Wang
- Department of Applied Physical Sciences, University of North Carolina at Chapel Hill
- Hany M. Arafa
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Quansan Yang
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Di Lu
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Shuo Li
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Lin Zhang
- Department of Applied Physical Sciences, University of North Carolina at Chapel Hill
- Xun Xiao
- Department of Applied Physical Sciences, University of North Carolina at Chapel Hill
- Abraham Vázquez-Guardado
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Joanna Ciatti
- Querrey Simpson Institute for Bioelectronics, Northwestern University
- Elizabeth Dempsey
- Developmental Therapeutics Core, Northwestern University
- Nayereh Ghoreishi-Haack
- Developmental Therapeutics Core, Northwestern University
- Emily A. Waters
- Center for Advanced Molecular Imaging, Northwestern University
- Chad R. Haney
- Center for Advanced Molecular Imaging, Northwestern University
- Amanda M. Westman
- Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine
- Matthew R. MacEwan
- Department of Neurosurgery, Washington University School of Medicine
- Mitchell A. Pet
- Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine
- John A. Rogers
- Department of Materials Science and Engineering, Northwestern University
- DOI
- https://doi.org/10.1038/s41467-022-30594-z
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 12
Abstract
Although continuous monitoring of tissue oxygenation is critically important after tissue/organ graft procedures, current technologies have key limitations. Here, the authors develop a miniaturized, minimally invasive, self-anchoring optical probe and demonstrate continuous monitoring of oxygenation in porcine flap and organ models.