Disseminated histoplasmosis in a cat rescued in Fortaleza, Brazil, and successfully treated with itraconazole – First case report identified molecularly

Liliane Lima da Silva Lomônaco; Stefanie Bressan Waller; Marlete Brum Cleff; Angelita dos Reis Gomes; Barbara Wilka Leal Silva; Rosane de Oliveira Cruz; Talles Monte de Almeida; Amanda Leal de Vasconcellos; Wesley Lyeverton Correia Ribeiro; Renata Osório de Faria; Mário Carlos Araújo Meireles; Adriana de Queiroz Pinheiro; Paula Priscila Correia Costa

Medical Mycology Case Reports (Dec 2020)

Disseminated histoplasmosis in a cat rescued in Fortaleza, Brazil, and successfully treated with itraconazole – First case report identified molecularly

Liliane Lima da Silva Lomônaco,
Stefanie Bressan Waller,
Marlete Brum Cleff,
Angelita dos Reis Gomes,
Barbara Wilka Leal Silva,
Rosane de Oliveira Cruz,
Talles Monte de Almeida,
Amanda Leal de Vasconcellos,
Wesley Lyeverton Correia Ribeiro,
Renata Osório de Faria,
Mário Carlos Araújo Meireles,
Adriana de Queiroz Pinheiro,
Paula Priscila Correia Costa

Affiliations

Liliane Lima da Silva Lomônaco: Veterinarian Autonomous, Fortaleza/CE, Brazil
Stefanie Bressan Waller: Faculty of Veterinary, Federal University of Pelotas, Rua Campus Universitario, 1, Pelotas/RS, 96010-900, Brazil; Corresponding author.
Marlete Brum Cleff: Faculty of Veterinary, Federal University of Pelotas, Rua Campus Universitario, 1, Pelotas/RS, 96010-900, Brazil
Angelita dos Reis Gomes: Faculty of Veterinary, Federal University of Pelotas, Rua Campus Universitario, 1, Pelotas/RS, 96010-900, Brazil
Barbara Wilka Leal Silva: Veterinarian Autonomous, Fortaleza/CE, Brazil
Rosane de Oliveira Cruz: Veterinarian Autonomous, Fortaleza/CE, Brazil
Talles Monte de Almeida: Veterinarian Autonomous, Fortaleza/CE, Brazil
Amanda Leal de Vasconcellos: Faculty of Veterinary, Ceará State University, Av. Dr. Silas Munguba, 1700, Campus Do Itaperi, Fortaleza/CE, 60714-903, Brazil
Wesley Lyeverton Correia Ribeiro: Department of Physiology and Pharmacology, Federal University of Ceará, Rua Cel. Nunes de Melo, 1127, Rodolfo Teófilo, Fortaleza/CE, 6430-275, Brazil
Renata Osório de Faria: Faculty of Veterinary, Federal University of Pelotas, Rua Campus Universitario, 1, Pelotas/RS, 96010-900, Brazil
Mário Carlos Araújo Meireles: Faculty of Veterinary, Federal University of Pelotas, Rua Campus Universitario, 1, Pelotas/RS, 96010-900, Brazil
Adriana de Queiroz Pinheiro: Faculty of Veterinary, Ceará State University, Av. Dr. Silas Munguba, 1700, Campus Do Itaperi, Fortaleza/CE, 60714-903, Brazil
Paula Priscila Correia Costa: Faculty of Veterinary, Federal University of Pelotas, Rua Campus Universitario, 1, Pelotas/RS, 96010-900, Brazil; Faculty of Veterinary, Ceará State University, Av. Dr. Silas Munguba, 1700, Campus Do Itaperi, Fortaleza/CE, 60714-903, Brazil

Journal volume & issue: Vol. 30
pp. 29 – 34

Abstract

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An unneutered female cat of unknown age presented bloody lesions on the edematous face, and respiratory signs. Cytology and culture from the skin sample collected with fine-needle aspiration showed yeasts inside activated macrophages, and fungal growth characteristic of Histoplasma spp., which was molecularly confirmed that was Histoplasma capsulatum var. capsulatum. The cat was successfully treated with oral itraconazole (10 mg/kg/daily) for 120 days. This is the first case report of feline histoplasmosis confirmed molecularly in Brazil.

Published in Medical Mycology Case Reports

ISSN: 2211-7539 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Medicine (General); Science: Biology (General)
Website: https://www.journals.elsevier.com/medical-mycology-case-reports/

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