Cryptogenic invasive klebsiella pneumonia liver abscess (cikpla) syndrome

Abstract

Escherichia coli, as the predominant pathogen in pyogenic liver abscess, resulting from underlying ascending hepatobiliary disease is well recognized. Klebsiella pneumoniae is a common pathogen responsible for diverse nosocomial and community-acquired infections, and is the third most common pathogen (10%) found in cases of nosocomial bacteremia, after Escherichia coli (20%) and Staphylococcus aureus (16.5%). Klebsiella pneumoniae has emerged as a major cause of primary or cryptogenic liver abscess with the recognition of the Cryptogenic Invasive Klebsiella Pneumoniae Liver Abscess Syndrome (CIKPLA). The syndrome appears to target populations of Asian descent with underlying disorders reflecting an impaired immunity, and is associated with the K1 hyper viscous serotype of this organism. We report a case of the CIKPLA syndrome, thus highlighting its continued evolution.

Keywords

• CIKPLA syndrome
• klebsiella
• liver abscess
• pneumonia