Effects of rivastigmine and memantine alone and
in combination on learning and memory in rats
with scopolamine-induced amnesia

Yanev Peter Georgiev; Dimitrova Darinka Slavcheva; Getova-Spassova Damianka Peteva

doi:10.1515/med-2015-0050

Open Medicine (Sep 2015)

Effects of rivastigmine and memantine alone and in combination on learning and memory in rats with scopolamine-induced amnesia

Yanev Peter Georgiev,
Dimitrova Darinka Slavcheva,
Getova-Spassova Damianka Peteva

Affiliations

Yanev Peter Georgiev: College of William and Mary, Williamsburg, Virginia 23187, USA
Dimitrova Darinka Slavcheva: Department of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Medical University, Plovdiv 4002, Bulgaria
Getova-Spassova Damianka Peteva: Department of Pharmacology, Medical Faculty, Medical University, 15A V. Aprilov str, Plovdiv 4002, Bulgaria

DOI: https://doi.org/10.1515/med-2015-0050
Journal volume & issue: Vol. 10, no. 1

Abstract

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Background: Cholinesterase inhibitors and glutamate blockers are commonly used for the treatment of cognitive impairment in Alzheimer’s disease. The aim was to evaluate the effects of rivastigmine and memantine alone or in combination in rats with scopolamine-impaired memory.

Published in Open Medicine

ISSN: 2391-5463 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine
Website: https://www.degruyter.com/journal/key/med/html

About the journal

Abstract

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