Role of RBC labeled 99m-Tc scan, Histopathology and Immunohistochemistry in Diagnosis of Jejunal Gastrointestinal Stromal Tumor presenting as obscure gastrointestinal haemorrhage

Abstract

Gastrointestinal stromal tumors (GIST) are relatively rare tumors of gastrointestinal (GI) tract, most commonly arise from the stomach followed by small intestine and colon, clinically GIST present with occult GI bleeding, abdominal pain and intestinal obstruction. We present a case of a jejunal GIST, which presented as an obscure GI haemorrhage. This case highlights how oesophagogastrodudenectomy and colonoscopy proved inconclusive in determining source of bleeding and the importance of RBC labeled 99m-Tc scan in detecting the source of GI bleeding and also emphasizes on histopathology and immunohistochemistry in diagnosis of GIST.

Keywords

• Gastrointestinal stromal tumor
• RBC labeled 99m-Tc scan
• Immunohistochemistry