Protective effects of N-acetyl-l-cysteine against penconazole-triggered hepatorenal toxicity in adult rats

Morgan Ashraf M.; Ogaly Hanan A.; Kamel Shaimaa; Rashad Maha M.; Hassanen Eman I.; Ibrahim Marwa A.; Galal Mona K.; Yassin Aya M.; Dulmani Sharah A. Al; Al-Zahrani Fatimah A.M.; Hussien Ahmed M.

doi:10.2478/jvetres-2023-0039

Journal of Veterinary Research (Sep 2023)

Protective effects of N-acetyl-l-cysteine against penconazole-triggered hepatorenal toxicity in adult rats

Morgan Ashraf M.,
Ogaly Hanan A.,
Kamel Shaimaa,
Rashad Maha M.,
Hassanen Eman I.,
Ibrahim Marwa A.,
Galal Mona K.,
Yassin Aya M.,
Dulmani Sharah A. Al,
Al-Zahrani Fatimah A.M.,
Hussien Ahmed M.

Affiliations

Morgan Ashraf M.: 1Toxicology and Forensic Medicine Department, 12211Giza, Egypt
Ogaly Hanan A.: 2Chemistry Department, Faculty of Science, King Khalid University, Abha 62421, Abha High City, Saudi Arabia
Kamel Shaimaa: 3Biochemistry and Molecular Biology Department, 12211Giza, Egypt
Rashad Maha M.: 3Biochemistry and Molecular Biology Department, 12211Giza, Egypt
Hassanen Eman I.: 4Pathology Department, Faculty of Veterinary Medicine, Cairo University, 12211Giza, Egypt
Ibrahim Marwa A.: 3Biochemistry and Molecular Biology Department, 12211Giza, Egypt
Galal Mona K.: 3Biochemistry and Molecular Biology Department, 12211Giza, Egypt
Yassin Aya M.: 3Biochemistry and Molecular Biology Department, 12211Giza, Egypt
Dulmani Sharah A. Al: 2Chemistry Department, Faculty of Science, King Khalid University, Abha 62421, Abha High City, Saudi Arabia
Al-Zahrani Fatimah A.M.: 2Chemistry Department, Faculty of Science, King Khalid University, Abha 62421, Abha High City, Saudi Arabia
Hussien Ahmed M.: 1Toxicology and Forensic Medicine Department, 12211Giza, Egypt

DOI: https://doi.org/10.2478/jvetres-2023-0039
Journal volume & issue: Vol. 67, no. 3
pp. 459 – 469

Abstract

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Penconazole (PEN) is a widely applied triazole fungicide. This study sought to define the efficacy of N-acetyl-l-cysteine (NAC) in mitigating PEN-triggered hepatorenal toxicity in rats.

Published in Journal of Veterinary Research

ISSN: 2450-8608 (Online)
Publisher: Sciendo
Country of publisher: Poland
LCC subjects: Agriculture: Animal culture: Veterinary medicine
Website: https://sciendo.com/journal/JVETRES

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Abstract

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