Influence of a macrolide antibiotic, roxithromycin, on mast cell growth and activation in vitro

Toshikazu  Shimane; Kazuhito  Asano; Mayumi  Suzuki; Tadashi  Hisamitsu; Harumi  Suzaki

doi:10.1080/09629350120102343

Mediators of Inflammation (Jan 2001)

Influence of a macrolide antibiotic, roxithromycin, on mast cell growth and activation in vitro

Toshikazu Shimane,
Kazuhito Asano,
Mayumi Suzuki,
Tadashi Hisamitsu,
Harumi Suzaki

Affiliations

Toshikazu Shimane: Department of Otolaryngology, School of Medicine, Showa University, 1–5–8 Hatanodai, Shinagawa-ku, Tokyo 142–8555, Japan
Kazuhito Asano: Department of Physiology, School of Medicine, Showa University, 1–5–8 Hatanodai, Shinagawa-ku, Tokyo 142–8555, Japan
Mayumi Suzuki: Department of Otolaryngology, School of Medicine, Showa University, 1–5–8 Hatanodai, Shinagawa-ku, Tokyo 142–8555, Japan
Tadashi Hisamitsu: Department of Physiology, School of Medicine, Showa University, 1–5–8 Hatanodai, Shinagawa-ku, Tokyo 142–8555, Japan
Harumi Suzaki: Department of Otolaryngology, School of Medicine, Showa University, 1–5–8 Hatanodai, Shinagawa-ku, Tokyo 142–8555, Japan

DOI: https://doi.org/10.1080/09629350120102343
Journal volume & issue: Vol. 10, no. 6
pp. 323 – 332

Abstract

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Background: Long-term administration of macrolide antibiotics is recognized to be able to favorably modify the clinical condition of inflammatory diseases, such as diffuse panbronchiolitis and cystic fibrosis. However, the precise mechanisms by which macrolide antibiotics could improve clinical conditions of the patients are not well understood.

Published in Mediators of Inflammation

ISSN: 0962-9351 (Print); 1466-1861 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Pathology
Website: https://onlinelibrary.wiley.com/journal/4792

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