Communications Biology (Apr 2022)

A functional SNP rs895819 on pre-miR-27a is associated with bipolar disorder by targeting NCAM1

  • Yifeng Yang,
  • Wenwen Lu,
  • Mei Ning,
  • Xianhao Zhou,
  • Xinyao Wan,
  • Qianglong Mi,
  • Xiaoyan Yang,
  • Di Zhang,
  • Yuanyuan Zhang,
  • Biao Jiang,
  • Lin He,
  • Jia Liu,
  • Yan Zou

DOI
https://doi.org/10.1038/s42003-022-03263-6
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 12

Abstract

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A T/C variant in miR-27a is associated with bipolar disorder, potentially by reducing the ability of this microRNA to target important neurodevelopmental genes like NCAM1.