A Simple and Efficient Synthesis of Highly Substituted Indeno[1,2-<i>b</i>]pyrrole and Acenaphtho[1,2-<i>b</i>]pyrrole Derivatives by Tandem Three-Component Reactions

Abstract

A green, convenient and tandem procedure for the efficient synthesis of highly substituted indeno[1,2-b]pyrrole and acenaphtho[1,2-b]pyrrole derivatives by domino three-component reaction of tryptamine/benzylamine, 1,3-dicarbonyl compounds and ninhydrin/ acenaphthenequinone is described. The significant features of this procedure were characterized by mild reaction conditions, high yields, operational simplicity and it being environmentally benign.

Keywords

• multi-component reactions
• indeno[1,2-<i>b</i>]pyrroles
• acenaphtho[1,2-<i>b</i>]pyrroles