Dietary protein increases T-cell-independent sIgA production through changes in gut microbiota-derived extracellular vesicles

Abstract

Secretory IgA plays vital roles interfacing between the host immune system and the resident microbiota at the mucosal surface. Here the authors explore the effect of dietary protein on the production of secretory IgA, driven by the production of extracellular vesicles by the intestinal microbiota.