Nature Communications (May 2022)

A 3D gene expression atlas of the floral meristem based on spatial reconstruction of single nucleus RNA sequencing data

  • Manuel Neumann,
  • Xiaocai Xu,
  • Cezary Smaczniak,
  • Julia Schumacher,
  • Wenhao Yan,
  • Nils Blüthgen,
  • Thomas Greb,
  • Henrik Jönsson,
  • Jan Traas,
  • Kerstin Kaufmann,
  • Jose M. Muino

DOI
https://doi.org/10.1038/s41467-022-30177-y
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

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Single-cell transcriptomics allows gene expression heterogeneity to be assessed at cellular resolution but the original location of each cell is unknown. Here the authors combine single nuclei RNA-seq with 3D spatial reconstruction of floral meristems to link gene activities with morphology.