Two New Triterpenoids from Photinia serrulata

Abstract

Two new triterpenoids, 2α,3β,11α,13β-tetrahydroxy-12-ketooleanan-28-oic acid(1) and 3β-hydroxy-12-keto-9(11)-ursen-28,13β-olide (2) were isolated from the leaves ofPhotinia serrulata. Their structures were identified by spectral methods. Compounds 1 and2 were assessed for cytotoxic activity against three human tumor cell lines (A-549, HCT-8,and BEL-7402), and they showed no cytotoxic effects at concentrations up to 5μg/mL.

Keywords

• Photinia serrulata
• Rosaceae
• triterpenoids
• cytotoxic activity