PLoS ONE (Jan 2015)

Easy to use plastic optical fiber-based biosensor for detection of butanal.

  • Nunzio Cennamo,
  • Stefano Di Giovanni,
  • Antonio Varriale,
  • Maria Staiano,
  • Fabio Di Pietrantonio,
  • Andrea Notargiacomo,
  • Luigi Zeni,
  • Sabato D'Auria

DOI
https://doi.org/10.1371/journal.pone.0116770
Journal volume & issue
Vol. 10, no. 3
p. e0116770

Abstract

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The final goal of this work is to achieve a selective detection of butanal by the realization of a simple, small-size and low cost experimental approach. To this end, a porcine odorant-binding protein was used in connection with surface plasmon resonance transduction in a plastic optical fiber tool for the selective detection of butanal by a competitive assay. This allows to reduce the cost and the size of the sensing device and it offers the possibility to design a "Lab-on-a-chip" platform. The obtained results showed that this system approach is able to selectively detect the presence of butanal in the concentration range from 20 μM to 1000 μM.