The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2

Ryan D. Chow; Medha Majety; Sidi Chen

doi:10.1038/s41467-020-20323-9

Nature Communications (Jan 2021)

The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2

Ryan D. Chow,
Medha Majety,
Sidi Chen

Affiliations

Ryan D. Chow: Department of Genetics, Yale University School of Medicine
Medha Majety: Department of Genetics, Yale University School of Medicine
Sidi Chen: Department of Genetics, Yale University School of Medicine

DOI: https://doi.org/10.1038/s41467-020-20323-9
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 13

Abstract

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Age is one of the strongest risk factors for severe illness from COVID-19. By integrating human lung transcriptomes with experimental data on SARS-CoV-2, the authors pinpoint specific age-associated factors that could contribute to the heightened severity of COVID-19 in older populations.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal