Stem Cell Research (Feb 2023)

Derivation of MUSIi016-A iPSCs from peripheral blood with blood type O Rh positive

  • Nittaya Jiamvoraphong,
  • Prapasri Septham,
  • Phatchanat Klaihmon,
  • Chuti Laowtammathron,
  • Yaowalak U-pratya,
  • Chanchao Lorthongpanich,
  • Surapol Issaragrisil

Journal volume & issue
Vol. 66
p. 103014

Abstract

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MUSIi016-A, a human induced pluripotent stem cell (iPSC), generated from peripheral blood mononuclear cells of a healthy blood group O Rh positive donor was reprogrammed using Sendai viral vectors containing Yamanaka’s factors. MUSIi016-A iPSC showed pluripotent stem cell characteristics, highly expressed pluripotent markers, and a capacity to differentiate into all three embryonic cell lineages. This iPSC can be used as a model for the generation of blood cells in vitro.