Localised prostate cancer and hemophilia A (AHA): Case report and management of the disease

Abstract

Acquired Hemophilia A (AHA) is a rare bleeding diathesis characterized by the development of autoantibodies against factor VIII (FVIII). About half of the cases are idiopathic and the other half are associated with autoimmune diseases, postpartum problems, infections, inflammatory bowel disease, drugs, lymphoproliferative disorders or solid tumors . AHA is associated with malignancies in 7-15% of cases. We report a case of AHA in a 65 year old patient with prostatic carcinoma, who underwent retropubic radical prostatectomy (RP).

Keywords

• Activated partial thromboplastin time
• Factor VIII
• Hemophilia A
• Prostate cancer
• Radical prostatectomy