The influence of HRT on bone mineral dencity, condition of parodontal complex tissue, clinical implications of articulated syndrome in postmenopausal women

Abstract

Introduction. To evaluate the effect of hormone replacement therapy on periodontal treatment outcomes complex, bone mineral density and articular syndrome in a group of postmenopausal women.Materials and methods. We carried out an exploration of 32 postmenopausal women aged 50-59 years , with chronic periodontitis, postmenopausal osteoporosis, hand osteoarthritis. The control group (n=14) didn’t receive HRT (HRT–). The test group (n=18) –received HRT (HRT+).All subjects were examined by recording the following: plaque index (PI), sulcus bleeding index (SBI), periodontal pocket depth (PD), Dreiser`s index, VAS pain score. Measurements were recorded at the baseline, 1 month, 3 months, and 6 monthsю Results. The significant decline was revealed in all of the values (PI, SBI, PD) in HRT+ compare to HRT-. After 6, 12 months, in the periodontal area had been stabilized in the HRT+ group. 11.2% reduction was indicated in the lumbar spine and 8,15% reduction in the femoral neck within the HRTafter 1 year. The significant decrease was discovered in VAS pain score, Dreiser`s index, painful joints quantity in HRT+.Conclusions: 12-week HRT was highly effective in periodontal treatment outcomes (significant decrease in PI, SBI, PD after 3 months). BMD of the femoral neck and lumbar spine is reduced within 1 year in patients with MHTcompared with MHT +.In the group of MHT +, compared with the group of MHTand baseline data, after 3 months there was a significant improvement in the number of painful joints, the level of pain, the Dreiser index, a positive effect persists until the end of the study.

Keywords

• hormone replacement therapy
• periodontitis
• osteopenia
• bone mineral density
• postmenopause