PATHOGENESIS OF DERMATITIS OF DEMODECOSIS ETIOLOGY IN DOGS

Abstract

Issues on demodecosis infection in dog population of Moscow have been studied; the dependence between the accents in the pathogenesis and the age and dog breed has been determined. The risk of acute demodecosis increases with the age, and in female dogs such risk goes up during their heat cycles. Biochemical values of the damage to internal organs: the total protein, glucose, urea, creatinine, activity of aspartate aminotransferase (AST) and alanine transaminase (ALT) in dogs’ blood have been estimated. In dogs with low and medium infection rates the average AST and ALT values were 51,05±2,64 and 98,69±3,85 u/l respectively, with a high infection rate 57,31±2,91 and 131,09±3,65 u/l. The increase of creatinine level and decrease in blood glucose of all tested dogs’ groups were observed. The most significant changes were determined in the levels of creatinine and glucose: up to 87,41±3,85 mkmol and 3,91±0,21 mmol respectively. Demodecosis should be considered as a complex issue requiring a detailed examination of enzyme levels and hormonal status.

Keywords

• demodecosis
• biochemical values
• pathogenesis
• dogs