Rational design of pyrrole derivatives with aggregation-induced phosphorescence characteristics for time-resolved and two-photon luminescence imaging

Jianhui Yang; Yahui Zhang; Xinghui Wu; Wenbo Dai; Dan Chen; Jianbing Shi; Bin Tong; Qian Peng; Haiyan Xie; Zhengxu Cai; Yuping Dong; Xin Zhang

doi:10.1038/s41467-021-25174-6

Nature Communications (Aug 2021)

Rational design of pyrrole derivatives with aggregation-induced phosphorescence characteristics for time-resolved and two-photon luminescence imaging

Jianhui Yang,
Yahui Zhang,
Xinghui Wu,
Wenbo Dai,
Dan Chen,
Jianbing Shi,
Bin Tong,
Qian Peng,
Haiyan Xie,
Zhengxu Cai,
Yuping Dong,
Xin Zhang

Affiliations

Jianhui Yang: Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of Technology
Yahui Zhang: School of Life Science, Advanced Research Institute of Multidisciplinary Science, Beijing Institute of Technology
Xinghui Wu: Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of Technology
Wenbo Dai: Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of Technology
Dan Chen: Department of Gynaecology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital
Jianbing Shi: Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of Technology
Bin Tong: Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of Technology
Qian Peng: School of Chemical Sciences, University of Chinese Academy of Sciences
Haiyan Xie: School of Life Science, Advanced Research Institute of Multidisciplinary Science, Beijing Institute of Technology
Zhengxu Cai: Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of Technology
Yuping Dong: Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of Technology
Xin Zhang: Department of Gynaecology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital

DOI: https://doi.org/10.1038/s41467-021-25174-6
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 8

Abstract

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Aggregation-induced emission (AIE) fluorescence probes are indispensable for biomedical imaging, however, interference with tissue autofluorescence results in low signal-to-noise ratio limiting the development of bioimaging with AIE materials. Here the authors develop AIEgen room-temperature phosphors with long emission lifetimes efficiently eliminating intereference with the background signal in imaging.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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