Human Respiratory Syncytial Virus Subgroup A and B Infections in Nasal, Bronchial, Small-Airway, and Organoid-Derived Respiratory Cultures

L. C. Rijsbergen; M. M. Lamers; A. D. Comvalius; R. W. Koutstaal; D. Schipper; W. P. Duprex; B. L. Haagmans; R. D. de Vries; R. L. de Swart

doi:10.1128/mSphere.00237-21

mSphere (Jun 2021)

Human Respiratory Syncytial Virus Subgroup A and B Infections in Nasal, Bronchial, Small-Airway, and Organoid-Derived Respiratory Cultures

L. C. Rijsbergen,
M. M. Lamers,
A. D. Comvalius,
R. W. Koutstaal,
D. Schipper,
W. P. Duprex,
B. L. Haagmans,
R. D. de Vries,
R. L. de Swart

Affiliations

L. C. Rijsbergen: Department of Viroscience, Postgraduate School of Molecular Medicine, Erasmus MC, Rotterdam, the Netherlands
M. M. Lamers: Department of Viroscience, Postgraduate School of Molecular Medicine, Erasmus MC, Rotterdam, the Netherlands
A. D. Comvalius: Department of Viroscience, Postgraduate School of Molecular Medicine, Erasmus MC, Rotterdam, the Netherlands
R. W. Koutstaal: Department of Viroscience, Postgraduate School of Molecular Medicine, Erasmus MC, Rotterdam, the Netherlands
D. Schipper
W. P. Duprex: ORCiD; Center for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
B. L. Haagmans: ORCiD; Department of Viroscience, Postgraduate School of Molecular Medicine, Erasmus MC, Rotterdam, the Netherlands
R. D. de Vries: ORCiD; Department of Viroscience, Postgraduate School of Molecular Medicine, Erasmus MC, Rotterdam, the Netherlands
R. L. de Swart: ORCiD; Department of Viroscience, Postgraduate School of Molecular Medicine, Erasmus MC, Rotterdam, the Netherlands

DOI: https://doi.org/10.1128/mSphere.00237-21
Journal volume & issue: Vol. 6, no. 3

Abstract

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Human respiratory syncytial virus (HRSV) is the major cause of bronchiolitis and pneumonia in young infants and causes almost 200,000 deaths per year. Currently, there is no vaccine or treatment available, only a prophylactic monoclonal antibody (palivizumab).

Published in mSphere

ISSN: 2379-5042 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msphere

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