Briareolate Esters from the Gorgonian <em>Briareum asbestinum</em>

Abstract

Two new briarane diterpenoids briareolate esters J (<strong>1</strong>) and K (<strong>2</strong>) were isolated from the methanolic extract of the octocoral <em>Briareum</em><em> asbestinum </em>collected off the coast of Boca Raton, Florida. The structures of briaranes <strong>1</strong> and <strong>2</strong> were elucidated by interpretation of spectroscopic data. Briareolate ester K (<strong>2</strong>) showed weak growth inhibition activity against human embryonic stem cells (BG02).

Keywords

• &lt;em&gt;Briareum asbestinum&lt;/em&gt;
• octocoral
• briarane
• briareolate ester
• human embryonic stem cell