Computerised tomography brain findings in male patients with alcohol dependence syndrome: A hospital based cross sectional study

Abstract

Background: Alcohol dependence syndrome (ADS) is a set of mental, emotional and physiological effects of drinking alcohol daily. This study aimed to assess the computerised tomography (CT) brain findings in patients with ADS and to compare it with age-matched controls. Aims: To study the relationship of CT-Brain findings in Male patients with alcohol dependence syndrome and compare it with controls. Materials and Methods: This retrospective study was carried out after obtaining clearance from the institution's ethics committee between 1 January 2021 and April 2022. Medical records of 64 patients were examined, of which 32 patients with the diagnosis of ADS who had already undergone CT brain Neuroimaging and 32 age- and sex-matched normal controls, were randomly selected and parameters were compared to look at cortical atrophy, cella media index (CMI), the maximum width of the third, fourth ventricle, frontal subarachnoid space, Evans ratio, the maximum width of the anterior interhemispheric fissure and maximum width of the Sylvian fissure (MSF). Results: The study detected that the mean age of cases was 41.96 years, and in controls, it was 40.91 years with no significant difference. There was a significant difference in the mean level of CMI, the maximum width of the third and fourth ventricle, frontal subarachnoid space, the maximum width of the anterior hemispheric fissure and the MSF amongst the cases compared to controls. Conclusion: Compared to controls, there was a significant change in CT brain findings amongst the ADS patients.

Keywords

• alcohol dependence syndrome
• computerised tomography brain
• neuroimaging