Nature Communications (Mar 2021)
Metabolic responses to mild cold acclimation in type 2 diabetes patients
- Carlijn M. E. Remie,
- Michiel P. B. Moonen,
- Kay H. M. Roumans,
- Emmani B. M. Nascimento,
- Anne Gemmink,
- Bas Havekes,
- Gert Schaart,
- Esther Kornips,
- Peter J. Joris,
- Vera B. Schrauwen-Hinderling,
- Joris Hoeks,
- Sander Kersten,
- Matthijs K. C. Hesselink,
- Esther Phielix,
- Wouter D. van Marken Lichtenbelt,
- Patrick Schrauwen
Affiliations
- Carlijn M. E. Remie
- Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center
- Michiel P. B. Moonen
- Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center
- Kay H. M. Roumans
- Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center
- Emmani B. M. Nascimento
- Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center
- Anne Gemmink
- Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center
- Bas Havekes
- Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center
- Gert Schaart
- Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center
- Esther Kornips
- Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center
- Peter J. Joris
- Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center
- Vera B. Schrauwen-Hinderling
- Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center
- Joris Hoeks
- Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center
- Sander Kersten
- Nutrition, Metabolism and Genomics Group, Division of Human Nutrition and Health, Wageningen University
- Matthijs K. C. Hesselink
- Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center
- Esther Phielix
- Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center
- Wouter D. van Marken Lichtenbelt
- Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center
- Patrick Schrauwen
- Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center
- DOI
- https://doi.org/10.1038/s41467-021-21813-0
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 10
Abstract
Cold acclimation has been shown to have beneficial metabolic effects, including improved insulin sensitivity in patients with type 2 diabetes. Here the authors show that a mild cold acclimation regiment during which overt shivering was prevented did not result in improved insulin sensitivity in a small group of patients with type 2 diabetes.