Ciência Rural (May 2016)

Epidemiological, clinical and diagnostic aspects of sheep conidiobolomycosis in Brazil

  • Carla Weiblen,
  • Daniela Isabel Brayer Pereira,
  • Valéria Dutra,
  • Isabela de Godoy,
  • Luciano Nakazato,
  • Luís Antonio Sangioni,
  • Janio Morais Santurio,
  • Sônia de Avila Botton

DOI
https://doi.org/10.1590/0103-8478cr20150935
Journal volume & issue
Vol. 46, no. 5
pp. 839 – 846

Abstract

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ABSTRACT: Conidiobolomycosis is an emerging disease caused by fungi of the cosmopolitan genus Conidiobolus . Particular strains of Conidiobolus coronatus, Conidiobolus incongruus and Conidiobolus lamprauges , mainly from tropical or sub-tropical origin, cause the mycosis in humans and animals, domestic or wild. Lesions are usually granulomatous and necrotic in character, presenting two clinical forms: rhinofacial and nasopharyngeal. This review includes the main features of the disease in sheep, with an emphasis on the epidemiology, clinical aspects, and diagnosis of infections caused by Conidiobolus spp. in Brazil. In this country, the disease is endemic in the Northeast and Midwest, affecting predominantly woolless sheep breeds and occasioning death in the majority of the studied cases. The species responsible for infections of sheep are C. coronatus and C. lamprauges and the predominant clinical presentation is nasopharyngeal. These fungal infections are very important, since they compromise the health status of the sheep flock and cause serious economic losses to the sheep industry. Thus, research is needed to investigate faster tools for diagnosis and effective methods for the control and treatment of conidiobolomycosis.

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