Biosynthesizing structurally diverse diols via a general route combining oxidative and reductive formations of OH-groups

Yongfei Liu; Wei Wang; An-Ping Zeng

doi:10.1038/s41467-022-29216-5

Nature Communications (Mar 2022)

Biosynthesizing structurally diverse diols via a general route combining oxidative and reductive formations of OH-groups

Yongfei Liu,
Wei Wang,
An-Ping Zeng

Affiliations

Yongfei Liu: Hamburg University of Technology, Institute of Bioprocess and Biosystems Engineering, Denickestrasse 15
Wei Wang: Hamburg University of Technology, Institute of Bioprocess and Biosystems Engineering, Denickestrasse 15
An-Ping Zeng: Hamburg University of Technology, Institute of Bioprocess and Biosystems Engineering, Denickestrasse 15

DOI: https://doi.org/10.1038/s41467-022-29216-5
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 15

Abstract

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Diols are important bulk and fine chemicals, but bioproduciton of branch-chain diols is hampered by the unknown biological route. Here, the authors report the expanding of amino acid metabolism for biosynthesis of branch-chain diols via a general route of combined oxidative and reductive formations of hydroxyl groups.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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