Nature Communications (Mar 2022)
Biosynthesizing structurally diverse diols via a general route combining oxidative and reductive formations of OH-groups
Abstract
Diols are important bulk and fine chemicals, but bioproduciton of branch-chain diols is hampered by the unknown biological route. Here, the authors report the expanding of amino acid metabolism for biosynthesis of branch-chain diols via a general route of combined oxidative and reductive formations of hydroxyl groups.