Subthreshold micropulse laser photocoagulation with intravitreous anti-VEGF for macular edema secondary to branch retinal vein occlusion

Abstract

AIM:To investigate the efficacy of subthreshold micropulse 577nm laser photocoagulation with intravitreous anti-vascular endothelial growth factor(anti-VEGF)treatment for macular edema secondary to branch retinal vein occlusion(BRVO). METHODS: A retrospective case series study was sixteen patients(16 eyes)of macular edema secondary to BRVO whose course was not more than 3mo were examined by fundus fluoresceine angiography(FFA)and optical coherence tomography(OCT). Eight eyes were given subthreshold micropulse 577nm laser with anti-VEGF treatment(micropulse laser group). Meantime another 8 eyes were given conventional grid laser photocoagulation with anti-VEGF treatment(grid laser group). The followed up was 6mo. The best corrected visual acuity(BCVA)and central foveal thickness(CFT)were analyzed.RESULTS: The baseline BCVA of the micropulse laser group was 0.34±0.18(LogMAR)and was improved to 0.07±0.01(PPPPP>0.05).CONCLUSION: Subthreshold micropulse 577nm laser with anti-VEGF and conventional grid laser photocoagulation with anti-VEGF had equivalent effects on the treatment of macular edema secondary to BRVO.

Keywords

• retinal vein occlusion
• subthreshold micropulse laser
• conventional grid laser photocoagulation
• curative effect
• curative effect