PLoS ONE (Jan 2020)

Association between platelet distribution width and prognosis in patients with heart failure.

  • Yu Sato,
  • Akiomi Yoshihisa,
  • Koichiro Watanabe,
  • Yu Hotsuki,
  • Yusuke Kimishima,
  • Tetsuro Yokokawa,
  • Tomofumi Misaka,
  • Takamasa Sato,
  • Takashi Kaneshiro,
  • Masayoshi Oikawa,
  • Atsushi Kobayashi,
  • Yasuchika Takeishi

DOI
https://doi.org/10.1371/journal.pone.0244608
Journal volume & issue
Vol. 15, no. 12
p. e0244608

Abstract

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BackgroundThe prognostic impact of platelet distribution width (PDW), which is a specific marker of platelet activation, has been unclear in patients with heart failure (HF).Methods and resultsWe conducted a prospective observational study enrolling 1,746 hospitalized patients with HF. Patients were divided into tertiles based on levels of PDW: 1st (PDW ConclusionsHigh PDW is a novel predictor of adverse prognosis in patients with HF.