Nature Communications (Sep 2016)
Simple direct formation of self-assembled N-heterocyclic carbene monolayers on gold and their application in biosensing
- Cathleen M. Crudden,
- J. Hugh Horton,
- Mina R. Narouz,
- Zhijun Li,
- Christene A. Smith,
- Kim Munro,
- Christopher J. Baddeley,
- Christian R. Larrea,
- Benedict Drevniok,
- Bheeshmon Thanabalasingam,
- Alastair B. McLean,
- Olena V. Zenkina,
- Iraklii I. Ebralidze,
- Zhe She,
- Heinz-Bernhard Kraatz,
- Nicholas J. Mosey,
- Lisa N. Saunders,
- Akiko Yagi
Affiliations
- Cathleen M. Crudden
- Department of Chemistry, Queen’s University
- J. Hugh Horton
- Department of Chemistry, Queen’s University
- Mina R. Narouz
- Department of Chemistry, Queen’s University
- Zhijun Li
- Department of Chemistry, Queen’s University
- Christene A. Smith
- Department of Chemistry, Queen’s University
- Kim Munro
- Protein Function Discovery Facility, Queen’s University
- Christopher J. Baddeley
- EaStCHEM School of Chemistry, University of St Andrews, St Andrews
- Christian R. Larrea
- EaStCHEM School of Chemistry, University of St Andrews, St Andrews
- Benedict Drevniok
- Department of Physics, Engineering Physics and Astronomy, Queen’s University
- Bheeshmon Thanabalasingam
- Department of Physics, Engineering Physics and Astronomy, Queen’s University
- Alastair B. McLean
- Department of Physics, Engineering Physics and Astronomy, Queen’s University
- Olena V. Zenkina
- Department of Chemistry, Queen’s University
- Iraklii I. Ebralidze
- Department of Chemistry, Queen’s University
- Zhe She
- Department of Physical and Environmental Sciences, University of Toronto Scarborough
- Heinz-Bernhard Kraatz
- Department of Physical and Environmental Sciences, University of Toronto Scarborough
- Nicholas J. Mosey
- Department of Chemistry, Queen’s University
- Lisa N. Saunders
- Department of Chemistry, Queen’s University
- Akiko Yagi
- Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University
- DOI
- https://doi.org/10.1038/ncomms12654
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 7
Abstract
Self-assembled monolayers (SAMs) have shown tremendous number of applications but can suffer from low stability. Here, the authors report air and bench stable carbene precursors allowing facile SAM formation, and furthermore demonstrate an application in biosensing