Nature Communications (Nov 2020)

Adaptive laboratory evolution of native methanol assimilation in Saccharomyces cerevisiae

  • Monica I. Espinosa,
  • Ricardo A. Gonzalez-Garcia,
  • Kaspar Valgepea,
  • Manuel R. Plan,
  • Colin Scott,
  • Isak S. Pretorius,
  • Esteban Marcellin,
  • Ian T. Paulsen,
  • Thomas C. Williams

DOI
https://doi.org/10.1038/s41467-020-19390-9
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 12

Abstract

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Methylotrophic metabolism enables growth on methanol, an alternative to sugar fermentation. Here the authors use adaptive laboratory evolution to uncover native methylotrophy capacity in Saccharomyces cerevisiae.