Síntese e caracterização de novos complexos de platina (II) com ligantes derivados do furano e nitrofurano Synthesis and characterization of new platinum (II) complexes containing furan and nitrofuran derived ligands

Abstract

Platinum (II) complexes, for example, cisplatin and carboplatin, have been used as chemotherapeutic agents for the treatment of various types of cancer. Several other complexes of this metallic ion are also under clinical evaluation. This work describes the synthesis of five new platinum (II) complexes having furan and 5-nitrofuran derivatives and chloride as ligands. The compounds were characterized by NMR, IR and elemental analysis.

Keywords

• platinum (II) complexes
• furan
• nitrofuran