Clinical Case Reports (Dec 2019)
Cauda equina syndrome in an ovarian malignant‐mixed müllerian tumor with leptomeningeal spread
- Joshua D. Bernstock,
- Stuart Ostby,
- Brandon Fox,
- Houman Sotoudeh,
- Andrew Janssen,
- Yun Jee Kang,
- Jason Chen,
- Veeranjaneyulu Prattipati,
- Galal Elsayed,
- Gustavo Chagoya,
- Daisuke Yamashita,
- Gregory K. Friedman,
- Burt Nabors,
- Warner K. Huh,
- Mina Lobbous
Affiliations
- Joshua D. Bernstock
- Department of Neurosurgery Brigham and Women's Hospital Harvard University Boston MA USA
- Stuart Ostby
- Division of Gynecologic Oncology University of Alabama at Birmingham Birmingham AL USA
- Brandon Fox
- School of Medicine University of Alabama at Birmingham Birmingham AL USA
- Houman Sotoudeh
- Department of Radiology, Neuroradiology Section University of Alabama at Birmingham Birmingham AL USA
- Andrew Janssen
- School of Medicine University of Alabama at Birmingham Birmingham AL USA
- Yun Jee Kang
- Harvard Medical School Boston MA USA
- Jason Chen
- Medical Scientist Training Program University of California Los Angeles CA USA
- Veeranjaneyulu Prattipati
- Department of Radiology, Neuroradiology Section University of Alabama at Birmingham Birmingham AL USA
- Galal Elsayed
- Department of Neurosurgery University of Alabama at Birmingham Birmingham AL USA
- Gustavo Chagoya
- Department of Neurosurgery University of Alabama at Birmingham Birmingham AL USA
- Daisuke Yamashita
- Department of Neurosurgery Brigham and Women's Hospital Harvard University Boston MA USA
- Gregory K. Friedman
- Division of Pediatric Hematology and Oncology Department of Pediatrics University of Alabama at Birmingham Birmingham AL USA
- Burt Nabors
- Department of Neurology University of Alabama at Birmingham Birmingham AL USA
- Warner K. Huh
- Division of Gynecologic Oncology University of Alabama at Birmingham Birmingham AL USA
- Mina Lobbous
- Department of Neurology University of Alabama at Birmingham Birmingham AL USA
- DOI
- https://doi.org/10.1002/ccr3.2472
- Journal volume & issue
-
Vol. 7,
no. 12
pp. 2341 – 2345
Abstract
Abstract Leptomeningeal metastasis is extremely rare in patients with ovarian cancer, but should be considered in patients presenting with neurologic deficits such as cauda equine syndrome. Given its poor prognosis and lack of data currently on management, additional studies are needed to optimize treatment regimens and improve outcomes.
Keywords
- cauda equina syndrome
- leptomeningeal carcinomatosis
- metastasis
- ovarian carcinosarcoma
- ovarian malignant‐mixed müllerian tumor
