mSystems (Aug 2021)

Recurrent Vulvovaginal Candidiasis: a Dynamic Interkingdom Biofilm Disease of <i>Candida</i> and <i>Lactobacillus</i>

  • Emily McKloud,
  • Christopher Delaney,
  • Leighann Sherry,
  • Ryan Kean,
  • Shanice Williams,
  • Rebecca Metcalfe,
  • Rachael Thomas,
  • Riina Richardson,
  • Konstantinos Gerasimidis,
  • Christopher J. Nile,
  • Craig Williams,
  • Gordon Ramage

DOI
https://doi.org/10.1128/mSystems.00622-21
Journal volume & issue
Vol. 6, no. 4

Abstract

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RVVC is a significant burden, both economically and for women's health, but its prevalence is poorly documented globally due to the levels of self-treatment. Identifying triggers for development and recurrence of VVC and the pathogenesis of the microbes involved could considerably improve prevention and treatment options for women with recurrent, azole-resistant cases.