Payesh (Dec 2020)
Interventions to improve Quality of Life in Patients with Major Thalassemia: A Systematic Review
Abstract
Objective (s): Thalassemia is the most common genetic disease can affect the quality of life of patients. The aim of this study was to evaluate the effect of interventions performed to improve quality of life of patients with major thalassemia. Methods: The present study was a systematic review. The following databases were included to identify relevant citations: Magiran, SID, ISC, IranMedex, Pubmed, Scopus, Google scholar, Web of Science, ProQuest and Cochrane using the keywords major thalassemia, quality of life, beta thalassemia, clinical research, Clinical trials based on Mesh were identified during July 2010 to July 2020. Articles were searched and extracted by two researchers independently. All articles that met the eligibility criteria were reviewed. Results: Out of 370 studies, finally 16 articles (5 Persian articles and 11 English articles) were reviewed, which were divided into five categories: psychological interventions (5 articles), health promotion education interventions (5 articles), and care interventions (3 articles), Empowerment interventions (2 articles) and physical activity (1 article). Most studies have confirmed the effectiveness of educational interventions in improving the quality of life of patients with major thalassemia. Conclusion: Educational interventions to improve the quality of life of patients with major thalassemia can have a positive effect and improve the quality of life of these people.
