Nature Communications (Jan 2021)

Concomitant control of mechanical properties and degradation in resorbable elastomer-like materials using stereochemistry and stoichiometry for soft tissue engineering

  • Mary Beth Wandel,
  • Craig A. Bell,
  • Jiayi Yu,
  • Maria C. Arno,
  • Nathan Z. Dreger,
  • Yen-Hao Hsu,
  • Anaïs Pitto-Barry,
  • Joshua C. Worch,
  • Andrew P. Dove,
  • Matthew L. Becker

DOI
https://doi.org/10.1038/s41467-020-20610-5
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 13

Abstract

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The creation of biomaterials which are resorbable and have biomimetic mechanical properties is key to successful tissue engineering. Here the authors report on the creation of a new biopolymer where the mechanical properties can be tuned by changing the ratios of cis:trans double bonds in the backbone.