Spectroscopic Studies of Delafloxacin Meglumine

Abstract

The structure of delafloxacin meglumine was analyzed by infrared absorption (IR), ultraviolet absorption (UV), nuclear magnetic resonance (1H NMR, 13C NMR, DEPT, 1H-1H COSY, 1H-13C HSQC and 1H-13C HMBC) spectroscopy, mass spectrometry and elemental analysis. The characteristic absorption peaks in the IR spectra were discussed. The 1H and 13C NMR signals of delafloxacin meglumine were assigned, and the two-dimensional signals were used to elucidate its structure. The crystal structure of delafloxacin meglumine was studied by differential scanning calorimetry (DSC), thermogravimetric analysis (TGA) and powder X-ray diffraction (PXRD).

Keywords

• delafloxacin meglumine
• nuclear magnetic resonance (nmr)
• infrared absorption spectroscopy
• structural elucidation
• crystal structure