Precisely translating computed tomography diagnosis accuracy into therapeutic intervention by a carbon-iodine conjugated polymer

Mingming Yin; Xiaoming Liu; Ziqiao Lei; Yuting Gao; Jiacheng Liu; Sidan Tian; Zhiwen Liang; Ye Wang; Fanling Meng; Liang Luo

doi:10.1038/s41467-022-30263-1

Nature Communications (May 2022)

Precisely translating computed tomography diagnosis accuracy into therapeutic intervention by a carbon-iodine conjugated polymer

Mingming Yin,
Xiaoming Liu,
Ziqiao Lei,
Yuting Gao,
Jiacheng Liu,
Sidan Tian,
Zhiwen Liang,
Ye Wang,
Fanling Meng,
Liang Luo

Affiliations

Mingming Yin: National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology
Xiaoming Liu: Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Ziqiao Lei: Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Yuting Gao: Faculty of Materials Science and Chemistry, China University of Geosciences
Jiacheng Liu: Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Sidan Tian: National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology
Zhiwen Liang: Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Ye Wang: Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Fanling Meng: National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology
Liang Luo: National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology

DOI: https://doi.org/10.1038/s41467-022-30263-1
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 12

Abstract

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Poly(diiododiacetylene)—PIDA—contains iodine atoms, which are commonly found in computed tomography contrast agents. Here, the authors find that PIDA can function as a contrast agent and can also be used as a visual marker to delineate tumour margins.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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