Blastic Plasmacytoid Dendritic Cell Neoplasia: A Rare Case Report

Abstract

Blastic Plasmacytoid Dendritic Cell Neoplasia (BPDCN) is a rare hematological malignancy whose pathogenesis has not yet been elucidated. Skin, bone marrow, and lymph node involvement can be observed, and it is generally seen in men and old adults. Immunohistochemistry (IHC) features of skin and bone marrow biopsy are essential for diagnosis. There are no standardized treatment options for this malignancy, and the prognosis is particularly poor. Although there are no standardized treatment options for this malignancy, multiple agent chemotherapies such as Hyper-CVAD and CHOP can be used. Bone marrow transplantation may be an option for patients with life expectancy. More case reports are required to understand and manage this extremely rare malignancy. We report the case we encountered in our clinic and selected CVP as the treatment approach.

Keywords

• blastic plasmacytoid dendritic cell neoplasia
• cutaneous lymphoma
• nk-cell lymphoma