Relationships Between Post-Endoscopıc Retrograde Cholangiopancreatography Pancreatitis and Preoperative Laboratory Parameters

Abstract

Purpose: Investigation of the relationship between post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis and laboratory tests performed before ERCP. Materials and Methods: ERCP procedures performed between March 2015 and June 2016 were analyzed retrospectively. Patient’s age, gender, ERCP indications, procedures performed during ERCP, complications after ERCP were determined. The relationship between post-ERCP pancreatitis and white blood cell, neutrophil, lymphocyte, hemoglobin, thrombocyte, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gama-glutamly transferase (GGT), total bilirubin, albumin, lactate dehydrogenase (LDH) values of the patients before the procedure was investigated. Results: GGT and AST levels in the preoperative period were lower in patients with pancreatitis compared to those who did not (GGT p=0.001, AST p=0.006). No significant difference was found in other parameters. Conclusion: Post-ERCP pancreatitis is the most common complication of ERCP. Detection of patients with risk factors for the development of pancreatitis is important for early diagnosis and treatment. AST level lesser than 1.5 times normal value and GGT level lesser than 4 times can be used in pre-operative pancreatitis risk assessment.

Keywords

• pancreatitis
• post-ercp
• risc factors