Nature Communications (Apr 2019)

4-Coumarate 3-hydroxylase in the lignin biosynthesis pathway is a cytosolic ascorbate peroxidase

  • Jaime Barros,
  • Luis Escamilla-Trevino,
  • Luhua Song,
  • Xiaolan Rao,
  • Juan Carlos Serrani-Yarce,
  • Maite Docampo Palacios,
  • Nancy Engle,
  • Feroza K. Choudhury,
  • Timothy J. Tschaplinski,
  • Barney J. Venables,
  • Ron Mittler,
  • Richard A. Dixon

DOI
https://doi.org/10.1038/s41467-019-10082-7
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 11

Abstract

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Lignin biosynthesis in higher plants relies upon a 3-hydroxylation reaction that can occur via shikimate esters of 4-coumarate. Here, Barros et al. define an alternative biosynthetic pathway via cytosolic ascorbate peroxidase that can catalyze direct 3-hydroxylation of 4-coumarate.