Nature Communications (Aug 2020)
De novo design of an intercellular signaling toolbox for multi-channel cell–cell communication and biological computation
- Pei Du,
- Huiwei Zhao,
- Haoqian Zhang,
- Ruisha Wang,
- Jianyi Huang,
- Ye Tian,
- Xudong Luo,
- Xunxun Luo,
- Min Wang,
- Yanhui Xiang,
- Long Qian,
- Yihua Chen,
- Yong Tao,
- Chunbo Lou
Affiliations
- Pei Du
- CAS Key Laboratory of Microbial, Physiological, and Metabolic Engineering and Institute of Microbiology, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences
- Huiwei Zhao
- CAS Key Laboratory of Microbial, Physiological, and Metabolic Engineering and Institute of Microbiology, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences
- Haoqian Zhang
- Bluepha Co., Ltd
- Ruisha Wang
- CAS Key Laboratory of Microbial, Physiological, and Metabolic Engineering and Institute of Microbiology, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences
- Jianyi Huang
- CAS Key Laboratory of Microbial, Physiological, and Metabolic Engineering and Institute of Microbiology, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences
- Ye Tian
- CAS Key Laboratory of Microbial, Physiological, and Metabolic Engineering and Institute of Microbiology, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences
- Xudong Luo
- CAS Key Laboratory of Microbial, Physiological, and Metabolic Engineering and Institute of Microbiology, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences
- Xunxun Luo
- CAS Key Laboratory of Microbial, Physiological, and Metabolic Engineering and Institute of Microbiology, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences
- Min Wang
- CAS Key Laboratory of Microbial, Physiological, and Metabolic Engineering and Institute of Microbiology, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences
- Yanhui Xiang
- CAS Key Laboratory of Quantitative Engineering Biology, Guangdong Provincial Key Laboratory of Synthetic Genomics, Shenzhen Key Laboratory of Synthetic Genomics, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences
- Long Qian
- Center for Quantitative Biology, Peking University
- Yihua Chen
- CAS Key Laboratory of Microbial, Physiological, and Metabolic Engineering and Institute of Microbiology, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences
- Yong Tao
- CAS Key Laboratory of Microbial, Physiological, and Metabolic Engineering and Institute of Microbiology, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences
- Chunbo Lou
- College of Life Science, University of Chinese Academy of Science
- DOI
- https://doi.org/10.1038/s41467-020-17993-w
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 11
Abstract
Intercellular signalling is fundamental for the formation of complex structures from single cells. Here the authors design six orthogonal cell–cell signalling channels for cell consortia communication and bio-computation.
