Frontiers in Pediatrics (Apr 2022)

Caregivers' Attitudes Toward COVID-19 Vaccination in Children and Adolescents With a History of SARS-CoV-2 Infection

  • Danilo Buonsenso,
  • Danilo Buonsenso,
  • Piero Valentini,
  • Piero Valentini,
  • Marina Macchi,
  • Francesco Folino,
  • Carola Pensabene,
  • Maria Francesca Patria,
  • Carlo Agostoni,
  • Carlo Agostoni,
  • Silvana Castaldi,
  • Silvana Castaldi,
  • Maurizio Lecce,
  • Maurizio Lecce,
  • Maria Lorella Giannì,
  • Maria Lorella Giannì,
  • Paola Marchisio,
  • Paola Marchisio,
  • Gregorio P. Milani,
  • Gregorio P. Milani,
  • The CHICO Study Group

DOI
https://doi.org/10.3389/fped.2022.867968
Journal volume & issue
Vol. 10

Abstract

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BackgroundLimited data are available on the attitudes of caregivers toward COVID-19 vaccination in children and adolescents with a history of SARS-CoV-2 infection or Long Covid symptoms. The aim of this study was to investigate the vaccine hesitancy among caregivers of children and adolescents with a documented history of SARS-CoV-2 infection and to explore the possible associations between COVID-19 manifestations and the acceptance of the vaccine.MethodsCaregivers of children or adolescents with a microbiologically confirmed diagnosis of SARS-CoV-2 infection evaluated in two University Hospitals were interviewed.ResultsWe were able to contact 132 caregivers and 9 declined to participate. 68 caregivers (56%) were in favor of COVID-19 vaccination for their child. In the multiple logistic regression, child's age (OR 1.17, 95%CI 1.06–1.28) and hospitalization due to COVID-19 (OR 3.25, 95%CI 1.06–9.95) were positively associated with being in favor of COVID-19 vaccination. On the contrary, the occurrence of child's Long Covid was associated with a higher likelihood of being against the vaccination (OR 0.28, 95%CI 0.10–0.80).ConclusionsThis preliminary study shows that only about half of the interviewed parents of children and adolescents with a previous SARS-CoV-2 infection are willing to vaccinate them to prevent a repeated COVID-19 infection. These findings might help healthcare workers to provide tailored information to caregivers of children with a previous SARS-CoV-2 infection.

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