Exploiting Poly(ethylene glycol) as a Matrix for Liquid-Phase Organic Synthesis

Abstract

Soluble polymer-supported chemistry is a technology that allows the blending of the benefits of polymer-supported synthesis and solution-phase chemistry. Herein, we describe our recent efforts in this area targeted at exploring the scope of poly(ethylene glycol) (PEG) as the matrix. Specifically we describe the use of PEG as a support for triphenyl phosphine and for the Stille reaction.

Keywords

• soluble polymer
• synthesis
• poly(ethylene glycol)
• triphenyl phosphine
• Wittig reaction
• Stille reaction