Nature Communications (Jul 2016)
An integrated genomic and transcriptomic survey of mucormycosis-causing fungi
- Marcus C. Chibucos,
- Sameh Soliman,
- Teclegiorgis Gebremariam,
- Hongkyu Lee,
- Sean Daugherty,
- Joshua Orvis,
- Amol C. Shetty,
- Jonathan Crabtree,
- Tracy H. Hazen,
- Kizee A. Etienne,
- Priti Kumari,
- Timothy D. O’Connor,
- David A. Rasko,
- Scott G. Filler,
- Claire M. Fraser,
- Shawn R. Lockhart,
- Christopher D. Skory,
- Ashraf S. Ibrahim,
- Vincent M. Bruno
Affiliations
- Marcus C. Chibucos
- Department of Microbiology and Immunology, University of Maryland School of Medicine
- Sameh Soliman
- Division of Infectious Diseases, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center
- Teclegiorgis Gebremariam
- Division of Infectious Diseases, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center
- Hongkyu Lee
- Division of Infectious Diseases, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center
- Sean Daugherty
- Institute for Genome Sciences, University of Maryland School of Medicine
- Joshua Orvis
- Institute for Genome Sciences, University of Maryland School of Medicine
- Amol C. Shetty
- Institute for Genome Sciences, University of Maryland School of Medicine
- Jonathan Crabtree
- Institute for Genome Sciences, University of Maryland School of Medicine
- Tracy H. Hazen
- Department of Microbiology and Immunology, University of Maryland School of Medicine
- Kizee A. Etienne
- Fungal Reference Laboratory, Mycotic Diseases Branch, Centers for Disease Control and Prevention
- Priti Kumari
- Institute for Genome Sciences, University of Maryland School of Medicine
- Timothy D. O’Connor
- Institute for Genome Sciences, University of Maryland School of Medicine
- David A. Rasko
- Department of Microbiology and Immunology, University of Maryland School of Medicine
- Scott G. Filler
- Division of Infectious Diseases, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center
- Claire M. Fraser
- Institute for Genome Sciences, University of Maryland School of Medicine
- Shawn R. Lockhart
- Fungal Reference Laboratory, Mycotic Diseases Branch, Centers for Disease Control and Prevention
- Christopher D. Skory
- National Center for Agriculture Utilization Research, USDA, Agricultural Research Service
- Ashraf S. Ibrahim
- Division of Infectious Diseases, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center
- Vincent M. Bruno
- Department of Microbiology and Immunology, University of Maryland School of Medicine
- DOI
- https://doi.org/10.1038/ncomms12218
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 11
Abstract
Fungi of the order Mucorales can cause life-threatening infections. Here, Chibucos et al. present genomic and transcriptomic analyses of a diverse set of Mucorales fungi, shedding light on their evolution and identifying potential therapeutic targets in the pathogens and the host.