The importance of serum LMAN2 level in septic shock and prognosis prediction in sepsis patients

Abstract

Objectives: To study the importance of LMAN2 in septic shock and prognosis prediction in sepsis patients. Methods: Serum LMAN2 was measured by ELISA in 109 sepsis patients within 24 h after their admission to ICU. We also collected clinical and laboratory variables. Results: Compared with sepsis group (1.21 (1.05) ng/ml), serum LMAN2 level was significantly higher in patients with septic shock (1.75 (2.04) ng/ml) on the day of admission to the ICU (P 1.28 ng/ml) was a predictor of 28-day mortality in sepsis patients. Conclusions: This study shows that high serum LMAN2 level may indicate septic shock and is associated with an unfavorable prognosis for sepsis patients.

Keywords

• Sepsis
• Septic shock
• LMAN2
• 28-Day mortality rate
• Glycocalyx