Efek Oksigen Konsentrasi Tinggi Pascaoperasi Laparotomi pada Peritonitis terhadap Tingkat Infeksi Luka Operasi

Abstract

A simple method to improve oxygen pressure to tissue perfusion adequately is by increasing the concentration of inspired oxygen.We therefore tested the hypothesis that the supplemental administration of oxygen during the post-operative period decreases the incidence of wound infection.We randomly assigned 102 patients at Dr. Hasan Sadikin Hospital who underwent exploratory laparotomy due to local and diffuse peritonitis to receive 30 percent or 80 percent inspired oxygen for two hours post-operation. The 30% oxygen was obtained from the nasal canule and 3 litres of oxygen whereas 80% oxygen was obtained from non-rebreathing mask and 10 litres of oxygen. Using the single-blind protocol, wounds were evaluated before the patients were discharged or 7 days post-operative and then two weeks after surgery. The clinical trial was performed at Dr. Hasan Sadikin Hospital Bandung between October 2009–May 2010. From the 51 patients who received 80% oxygen, 2 (4%) had surgical-wound infections, whereas from the 51 patients given 30 percent oxygen, 9 (18%) had surgical-wound infections. The length of hospital stay for both groups were the same. In conclusion that post-operative administration of high concentration ofoxygen can reduce the incidence of surgical-wound infections.

Keywords

• Laparotomy
• oxygen
• periotonitis
• surgical wound infection