Journal of Orthopaedic Reports (Dec 2025)

Antimicrobial resistance (AMR) in Orthopaedic surgeries: A Complex issue and global threat

  • Amit Lakhani,
  • Karan Jindal,
  • Kavin Khatri

Journal volume & issue
Vol. 4, no. 4
p. 100466

Abstract

Read online

Introduction: Antimicrobial resistance (AMR) in orthopedic surgeries presents significant challenges in terms of prevention, management, and outcomes. Orthopedic procedures, especially those involving implants, are highly susceptible to infections, which can be catastrophic when caused by resistant organisms. Causes: Antimicrobial resistance (AMR) in orthopedic surgeries is driven by several causes and contributing factors. These include prolonged hospital stay and increased use of implants (which can serve as surfaces for biofilm formation by resistant bacteria). Inadequate sterilization of surgical instruments and poor infection control practices further exacerbate the risk of introducing resistant organisms. Conclusions: Addressing AMR in orthopedics necessitates a multifaceted approach, including stringent antibiotic stewardship programs, robust infection control practices, and ongoing research into new antimicrobial agents and alternative treatments. This article provides detailed insights into AMR in the context of orthopedic surgeries. Implementing stricter antibiotic stewardship programs that emphasize appropriate prescribing based on culture and sensitivity testing is crucial.