Canadian Journal of Gastroenterology (Jan 2000)

Expression of Lewisa, Sialyl Lewisa, Lewisx, Sialyl Lewisx, Antigens as Prognostic Factors in Patients with Colorectal Cancer

  • Tohru Nakagoe,
  • Kiyoyasu Fukushima,
  • Atsushi Nanashima,
  • Terumitsu Sawai,
  • Takashi Tsuji,
  • Masaaki Jibiki,
  • Hiroyuki Yamaguchi,
  • Toru Yasutake,
  • Hiroyoshi Ayabe,
  • Tatsuki Matuo,
  • Yutaka Tagawa,
  • Kokichi Arisawa

DOI
https://doi.org/10.1155/2000/149851
Journal volume & issue
Vol. 14, no. 9
pp. 753 – 760

Abstract

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BACKGROUND: Altered expression of blood group-related carbohydrate antigens such as sialyl Lewis (Le)x antigen in tumours is associated with tumour progression behaviour and subsequent prognosis. However, the prognostic value of the expression of Le-related antigens in colorectal tumours remains unclear.