Canadian Journal of Gastroenterology (Jan 2000)
Expression of Lewisa, Sialyl Lewisa, Lewisx, Sialyl Lewisx, Antigens as Prognostic Factors in Patients with Colorectal Cancer
Abstract
BACKGROUND: Altered expression of blood group-related carbohydrate antigens such as sialyl Lewis (Le)x antigen in tumours is associated with tumour progression behaviour and subsequent prognosis. However, the prognostic value of the expression of Le-related antigens in colorectal tumours remains unclear.