Nature Communications (Jun 2021)

Attention-based multi-label neural networks for integrated prediction and interpretation of twelve widely occurring RNA modifications

  • Zitao Song,
  • Daiyun Huang,
  • Bowen Song,
  • Kunqi Chen,
  • Yiyou Song,
  • Gang Liu,
  • Jionglong Su,
  • João Pedro de Magalhães,
  • Daniel J. Rigden,
  • Jia Meng

DOI
https://doi.org/10.1038/s41467-021-24313-3
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 11

Abstract

Read online

RNA modifications appear to play a role in determining RNA structure and function. Here, the authors develop a deep learning model that predicts the location of 12 RNA modifications using primary sequence, and show that several modifications are associated, which suggests dependencies between them.