Drug resistance mechanism and therapeutic schedule of Mycobacterium tuberculosis

Abstract

Mycobacterium tuberculosis can attack many systems of people, such as central nervous system, respiratory system, urinary system, and so on. The fatality rate and disability rate of diseases caused by Mycobacterium tuberculosis are high and are rising in many areas of the world. Because of drug resistance, the diagnosis and therapy become harder. Consequently, it is of great importance for us to understand drug resistance mechanism and make an effective therapeutic schedule, so that we can timely diagnose, effectively treat and improve outcomes. This article summarizes drug resistance mechanism of Mycobacterium tuberculosis against common anti-tuberculosis drugs and its therapeutic schedule. doi: 10.3969/j.issn.1672-6731.2014.08.005

Keywords

• Mycobacterium tuberculosis
• Antitubercular agents
• Drug tolerance
• Review