Brazilian Neurosurgery (Dec 2023)

Literature Review: Role of Neurosurgery in Leptomeningeal Carcinomatosis

  • Thaís Mitie Ogasawara,
  • Thaís Yumi Kobayashi Batista,
  • Rafael Rodrigues Pinheiro dos Santos,
  • Ana Carla Mondek Rampazzo,
  • Caroline Amane Pessoa Badaoui,
  • Igor Ruan de Araújo Caetano,
  • Jonathan Vinícius Martins,
  • Maria Letícia Nogueira,
  • José Ângelo Guarnieri,
  • Carlos Alexandre Martins Zicarelli

DOI
https://doi.org/10.1055/s-0042-1758210
Journal volume & issue
Vol. 42, no. 04
pp. e337 – e342

Abstract

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Introduction Leptomeningeal carcinomatosis results from metastatic neoplastic cells that reach the leptomeninges through the cerebrospinal fluid. The presentation of the disease is variable, making prognosis challenging. However, the presence of intracranial hypertension is common, which has prompted new treatments to mitigate this effect.

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